Policy Cures Research investigated the historic and current pipeline of drugs, biologics, and dietary supplements for the five pregnancy-related conditions.
The database includes any identified drug, biologic or dietary supplement that has been investigated (preclinically and/or clinically) for these pregnancy-related conditions since the year 2000. A total of 444 candidates were identified, including 11 candidates for fetal distress and 178 candidates for preterm labor.
Of these 444 candidates, 50% currently have an active status with a publication or new development in the past three years, and approximately 60% are repurposed medicines.
Half of the candidates are in preclinical development (48%), followed by Phase II and III (21-22%), and a total 24 and 17 candidates can be found in respectively Phase I and IV (4-5%).
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